Cystic fibrosis mutation involves which gene on which chromosome?

Cystic fibrosis mutation involves which gene on which chromosome?

• A. CFTR gene on chromosome 11
• B. CFTR gene on chromosome 7
• C. CFTR gene on chromosome 14
• D. CFTR gene on chromosome 19

Answer: (B)

Cystic fibrosis is caused by mutations in the CFTR gene, which encodes a chloride channel that helps regulate salt and water movement across epithelial surfaces. This gene is located on chromosome 7 (specifically at 7q31.2). When CFTR doesn’t function properly, chloride and water transport is disrupted, leading to thick, sticky mucus in the lungs, pancreas, and other organs. That’s why the correct pairing is CFTR on chromosome 7. The other chromosomes listed do not host the CFTR gene.

Cystic fibrosis is caused by mutations in the CFTR gene, which encodes a chloride channel that helps regulate salt and water movement across epithelial surfaces. This gene is located on chromosome 7 (specifically at 7q31.2). When CFTR doesn’t function properly, chloride and water transport is disrupted, leading to thick, sticky mucus in the lungs, pancreas, and other organs. That’s why the correct pairing is CFTR on chromosome 7. The other chromosomes listed do not host the CFTR gene.